摘要: Endocrinology, as a discipline, was late arrival in the corpus of established subjects. Its growth recent years has been prodigious, extending from mor- phology to molecular levels. Most major endocrine glands were noted by early anatomists, although adrenal not described until 1563 Bartholomaeus Eustachius (1520-1574). On other hand, elucidation function these extremely slow. Key work A. Berthold (1849), overlooked at time, showed that comb atrophy castrated fowl prevented testis transplantation. The idea produced substances reach- ing bloodstream directly and via excretory ducts stemmed Claude Bernard, who first used term internal secretion 1855. clinical observa- tions Thomas Addison Guy's Hospital-published monograph 1855 entitled Constitutional Local Effects Disease Suprarenal Capsules -were seminal. However, stimulus this research did bring imme- diate widespread further investigations. Upon discovery secretin 1902, Bayliss Starling considered "internal secretion" be clumsy, "hormone" coined (from OQ[!UW-1 excite or arouse) it his Croonian 1905.