Biosynthesis, Structure, and Function of Neuromelanin and its Relation to Parkinson's Disease: A Critical Update
作者： MARCO D'ISCHIA , GIUSEPPE PROTA
DOI: 10.1111/J.1600-0749.1997.TB00694.X
关键词:
摘要: No longer dismissed as just a mere curiosity in the family of melanin pigments, neuromelanin is attracting increasing interest central constituent certain populations dopaminergic neurons human substantia nigra, which may hold key for understanding neuron functioning and degeneration aging Parkinson's disease. It purpose this article to provide concise review most significant data on origin, structure, functional significance that accrued over past few years. also aims at critically surveying currently debated views regarding role such intriguing pigment etiology biochemical pathology
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