Primary myocardial disease. Clinical, hemodynamic and angiocardiographic correlates in fifty patients.

摘要: Fifty adult patients with primary myocardial disease were studied by clinical, hemodynamic and angiographic means. The divided into two groups on the basis of diastolic phase left ventricular pressure pulse. 24 in Group I had a normal pulse contour or elevated end-diastolic pressure, characterized presystolic prominent transmitted wave. 26 II abnormal elevation entire (congestive pattern); 9 this was accompanied an early dip plateau (restrictive pattern). There no significant differences age, sex, race chronic alcoholism between groups. Patients longer duration symptoms, increased frequency third heart sounds, apical systolic murmurs axis deviation. Patients resting hemodynamics except for filling ventricle (14 patients) right (9 patients), as well low stroke work. evidence biventricular dysfunction cardiac index, mean ejection rate, volume greater than those I, values both significantly (P < 0.001). Forty-two percent volume. wall thicker fraction lower II, normal. Predominant hypertrophy appeared to characterize condition predominant dilation that II. This further corroborated relations among cavity volume, thickness weight ventricle. circumferential stress tension whereas these indexes abnormally II. Our experience suggests there is latent asymptomatic stage followed symptomatic hypertrophic (Group I) which progresses irreversible dilatation II).