Challenges and opportunities in genome-wide environmental interaction (GWEI) studies

Marilyn C. Cornelis, Arpana Agrawal, John W. Cole, Nadia N. Hansel, Kathleen C. Barnes, Terri H. Beaty, Siiri N. Bennett, Laura J. Bierut, Eric Boerwinkle, Kimberly F. Doheny, Bjarke Feenstra, Eleanor Feingold, Myriam Fornage, Christopher A. Haiman, Emily L. Harris, M. Geoffrey Hayes, John A. Heit, Frank B. Hu, Jae H. Kang, Cathy C. Laurie, Hua Ling, Teri A. Manolio, Mary L. Marazita, Rasika A. Mathias, Daniel B. Mirel, Justin Paschall, Louis R. Pasquale, Elizabeth W. Pugh, John P. Rice, Jenna Udren, Rob M. van Dam, Xiaojing Wang, Janey L. Wiggs, Kayleen Williams, Kai Yu, The Gene, Environment Association Studies Consortium (GENEVA): Maximizing the Knowledge Obtained from GWAS by Collaboration Across Studies of Multiple Conditions Genetic Epidemiology. ,vol. 34, pp. 364- 372 ,(2010) , 10.1002/GEPI.20492

D. Li, D. V. Conti, Detecting Gene-Environment Interactions Using a Combined Case-Only and Case-Control Approach American Journal of Epidemiology. ,vol. 169, pp. 497- 504 ,(2008) , 10.1093/AJE/KWN339

Matthew J Maenner, Loren C Denlinger, Asher Langton, Kristin J Meyers, Corinne D Engelman, Halcyon G Skinner, Detecting gene-by-smoking interactions in a genome-wide association study of early-onset coronary heart disease using random forests. BMC Proceedings. ,vol. 3, pp. 1- 5 ,(2009) , 10.1186/1753-6561-3-S7-S88

Sophie van der Sluis, Conor V. Dolan, Michael C. Neale, Danielle Posthuma, A general test for gene-environment interaction in sib pair-based association analysis of quantitative traits Behavior Genetics. ,vol. 38, pp. 372- 389 ,(2008) , 10.1007/S10519-008-9201-8

Julia Ciampa, Meredith Yeager, Kevin Jacobs, Michael J. Thun, Susan Gapstur, Demetrius Albanes, Jarmo Virtamo, Stephanie J. Weinstein, Edward Giovannucci, Walter C. Willett, Geraldine Cancel-Tassin, Olivier Cussenot, Antoine Valeri, David Hunter, Robert Hoover, Gilles Thomas, Stephen Chanock, Chris Holmes, Nilanjan Chatterjee, Application of a Novel Score Test for Genetic Association Incorporating Gene-Gene Interaction Suggests Functionality for Prostate Cancer Susceptibility Regions Human Heredity. ,vol. 72, pp. 182- 193 ,(2011) , 10.1159/000331222

Abbas Dehghan, Josée Dupuis, Maja Barbalic, Joshua C Bis, Gudny Eiriksdottir, Chen Lu, Niina Pellikka, Henri Wallaschofski, Johannes Kettunen, Peter Henneman, Jens Baumert, David P Strachan, Christian Fuchsberger, Veronique Vitart, James F Wilson, Guillaume Paré, Silvia Naitza, Megan E Rudock, Ida Surakka, Eco JC De Geus, Behrooz Z Alizadeh, Jack Guralnik, Alan Shuldiner, Toshiko Tanaka, Robert YL Zee, Renate B Schnabel, Vijay Nambi, Maryam Kavousi, Samuli Ripatti, Matthias Nauck, Nicholas L Smith, Albert V Smith, Jouko Sundvall, Paul Scheet, Yongmei Liu, Aimo Ruokonen, Lynda M Rose, Martin G Larson, Ron C Hoogeveen, Nelson B Freimer, Alexander Teumer, Russell P Tracy, Lenore J Launer, Julie E Buring, Jennifer F Yamamoto, Aaron R Folsom, Eric JG Sijbrands, James Pankow, Paul Elliott, John F Keaney, Wei Sun, Antti-Pekka Sarin, João D Fontes, Sunita Badola, Brad C Astor, Albert Hofman, Anneli Pouta, Karl Werdan, Karin H Greiser, Oliver Kuss, Henriette E Meyer zu Schwabedissen, Joachim Thiery, Yalda Jamshidi, Ilja M Nolte, Nicole Soranzo, Timothy D Spector, Henry Völzke, Alexander N Parker, Thor Aspelund, David Bates, Lauren Young, Kim Tsui, David S Siscovick, Xiuqing Guo, Jerome I Rotter, Manuela Uda, David Schlessinger, Igor Rudan, Andrew A Hicks, Brenda W Penninx, Barbara Thorand, Christian Gieger, Joe Coresh, Gonneke Willemsen, Tamara B Harris, Andre G Uitterlinden, Marjo-Riitta Järvelin, Kenneth Rice, Dörte Radke, Veikko Salomaa, Ko Willems van Dijk, Eric Boerwinkle, Ramachandran S Vasan, Luigi Ferrucci, Quince D Gibson, Stefania Bandinelli, Harold Snieder, Dorret I Boomsma, Xiangjun Xiao, Harry Campbell, Caroline Hayward, Peter P Pramstaller, Cornelia M Van Duijn, Leena Peltonen, Bruce M Psaty, Vilmundur Gudnason, Paul M Ridker, Georg Homuth, Wolfgang Koenig, Christie M Ballantyne, Jacqueline CM Witteman, Emelia J Benjamin, Markus Perola, Daniel I Chasman, None, Meta-analysis of genome-wide association studies in >80,000 subjects identifies multiple loci for C-reactive protein levels Circulation. ,vol. 123, pp. 731- 738 ,(2011) , 10.1161/CIRCULATIONAHA.110.948570

Duncan Thomas, Methods for Investigating Gene-Environment Interactions in Candidate Pathway and Genome-Wide Association Studies Annual Review of Public Health. ,vol. 31, pp. 21- 36 ,(2010) , 10.1146/ANNUREV.PUBLHEALTH.012809.103619

M.H. Dizier, H. Selinger-Leneman, E. Genin, Testing linkage and gene x environment interaction: comparison of different affected sib-pair methods. Genetic Epidemiology. ,vol. 25, pp. 73- 79 ,(2003) , 10.1002/GEPI.10244

Sara Geneletti, Valentina Gallo, Miquel Porta, Muin J Khoury, Paolo Vineis, Assessing causal relationships in genomics: From Bradford-Hill criteria to complex gene-environment interactions and directed acyclic graphs Emerging Themes in Epidemiology. ,vol. 8, pp. 5- 5 ,(2011) , 10.1186/1742-7622-8-5

J. S. Witte, W. J. Gauderman, D. C. Thomas, Asymptotic Bias and Efficiency In Case-Control Studies of Candidate Genes and Gene-Environment Interactions: Basic Family Designs American Journal of Epidemiology. ,vol. 149, pp. 693- 705 ,(1999) , 10.1093/OXFORDJOURNALS.AJE.A009877