Impact of pneumococcal conjugate vaccines on childhood otitis media in the United Kingdom.
作者： Wallis CY Lau , Macey Murray , Aisha El-Turki , Sonia Saxena , Shamez Ladhani
DOI: 10.1016/J.VACCINE.2015.08.022
关键词:
摘要: Abstract Background Studies have demonstrated a reduction for otitis media (OM) following the introduction of seven-valent pneumococcal conjugate vaccine (PCV7), but this has not been evaluated in United Kingdom (UK). Moreover, there are limited data on any additional impact PCV13 2010. Methods We conducted an observational cohort study to investigate trends OM incidence and associated antibiotic prescriptions children aged Results Overall annual declined by 51.3% from 135.8 episodes/1000 person-years 2002 66.1 2012; prescription rates 72.9% 57.9 prescriptions/1000 15.7 person-years, respectively. PCV7 was with significant decline across all age-groups (21.8%; 95% CI, 20.2–23.4), including Conclusion The 22% reductions
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sci-hub.se 参考文章(35)
A. S. Lieberthal, A. E. Carroll, T. Chonmaitree, T. G. Ganiats, A. Hoberman, M. A. Jackson, M. D. Joffe, D. T. Miller, R. M. Rosenfeld, X. D. Sevilla, R. H. Schwartz, P. A. Thomas, D. E. Tunkel, The Diagnosis and Management of Acute Otitis Media Pediatrics. ,vol. 131, ,(2013) , 10.1542/PEDS.2012-3488
Alessia Melegaro, WJ Edmunds, Richard Pebody, Elizbeth Miller, Robert George, None, The current burden of pneumococcal disease in England and Wales. Journal of Infection. ,vol. 52, pp. 37- 48 ,(2006) , 10.1016/J.JINF.2005.02.008
K. A. Poehling, P. G. Szilagyi, C. G. Grijalva, S. W. Martin, B. LaFleur, E. Mitchel, R. D. Barth, J. P. Nuorti, M. R. Griffin, Reduction of Frequent Otitis Media and Pressure-Equalizing Tube Insertions in Children After Introduction of Pneumococcal Conjugate Vaccine Pediatrics. ,vol. 119, pp. 707- 715 ,(2007) , 10.1542/PEDS.2006-2138
P L Thompson, N Spyridis, M Sharland, R E Gilbert, S Saxena, P F Long, A P Johnson, I C K Wong, Changes in clinical indications for community antibiotic prescribing for children in the UK from 1996 to 2006: will the new NICE prescribing guidance on upper respiratory tract infections just be ignored? Archives of Disease in Childhood. ,vol. 94, pp. 337- 340 ,(2009) , 10.1136/ADC.2008.147579
Irene Petersen, Andrew C. Hayward, Antibacterial prescribing in primary care Journal of Antimicrobial Chemotherapy. ,vol. 60, pp. i43- i47 ,(2007) , 10.1093/JAC/DKM156
T. Q. Tan, Pediatric Invasive Pneumococcal Disease in the United States in the Era of Pneumococcal Conjugate Vaccines Clinical Microbiology Reviews. ,vol. 25, pp. 409- 419 ,(2012) , 10.1128/CMR.00018-12
S. Taylor, P. Marchisio, A. Vergison, J. Harriague, W. P. Hausdorff, M. Haggard, Impact of Pneumococcal Conjugate Vaccination on Otitis Media: A Systematic Review Clinical Infectious Diseases. ,vol. 54, pp. 1765- 1773 ,(2012) , 10.1093/CID/CIS292
G Gefenaite, M J Bijlsma, H J Bos, E Hak, Did introduction of pneumococcal vaccines in the Netherlands decrease the need for respiratory antibiotics in children? Analysis of 2002 to 2013 data. Eurosurveillance. ,vol. 19, pp. 10- 15 ,(2014) , 10.2807/1560-7917.ES2014.19.44.20948
Hsia YingFen Hsia YingFen, D Dawoud, AG Sutcliffe, RM Viner, Sanjay Kinra Sanjay Kinra, ICK Wong, Unlicensed use of metformin in children and adolescents in the UK British Journal of Clinical Pharmacology. ,vol. 73, pp. 135- 139 ,(2012) , 10.1111/J.1365-2125.2011.04063.X
Simon De Lusignan, Peter N Stephens, Naeema Adal, Azeem Majeed, Does Feedback Improve the Quality of Computerized Medical Records in Primary Care Journal of the American Medical Informatics Association. ,vol. 9, pp. 395- 401 ,(2002) , 10.1197/JAMIA.M1023