Dynamic hysteresis between gradient echo and spin echo attenuations in dynamic susceptibility contrast imaging

摘要: Perfusion measurements using dynamic susceptibility contrast imaging provide additional information about the mean vessel size of microvasculature when supplemented with a dual gradient echo (GE) – spin (SE) contrast. Dynamic increase in corresponding transverse relaxation rate constant changes, ΔR2GE and ΔR2SE, forms loop on (Δ, ΔR2GE) plane, rather than reversible line. The shape direction its passage differentiate between healthy brain pathological tissue, such as tumour ischemic tissue. By considering tree model microvasculature, is found to be influenced mainly by relative arterial venous blood volume, well tracer bolus dispersion. A parameter Λ proposed characterize loop, which might considered novel marker for describing pathology cerebrovascular network. Magn Reson Med 69:981–991, 2013. © 2012 Wiley Periodicals, Inc.