Mechanisms of Cooperativity and Allosteric Regulation in Proteins

作者: Max F. Perutz

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摘要: Preface 1. Introduction 2. Haemoglobin: Dependence of allosteric equilibrium on spin state and coordination the haem iron 3. Haemocyanin: valency a binuclear copper complex 4. Haemerythrin: Cooperativity in 5. Glycogen phosphorylase: Control glycolysis 6. Phosphofructokinase: Further control 7. Feedback inhibition biosynthetic pathway: Aspartate Transcarbamoylase 8. nitrogen metabolism: Glutamine synthetase 9. feedback without change quaternary structure: The "trp" "met" repressors E. Coli 10. Immunoglobulins: Cooperative binding to multivalent antigens 11. Allosteric membrane proteins.

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