Altered plasma levels of arginine metabolites in depression
作者： Arisoy Ozden , Halaris Angelos , Aricioglu Feyza , Wild Elizabeth , Piletz John
DOI: 10.1016/J.JPSYCHIRES.2019.10.004
关键词:
摘要: L-Arginine pathway metabolites appear to play differential roles in the pathogenesis of major depressive disorder (MDD). Studies have revealed an antidepressant and anxiolytic effect of agmatine and putrescine. Possible mechanisms of these effects include inhibition of nitric oxide synthase and N-methyl-D-aspartate receptors. The present study sought to determine whether MDD is associated with altered levels of arginine metabolites and whether these metabolites are associated with depression, anxiety and stress severity. Seventy seven …
sci-hub.se 参考文章(54)
J. E. Piletz, D. Hoppensteadt, J. Fareed, A. Halaris, O. Iqbal, C. L. DeVane, J. Sinacore, H. Zhu, Nitric oxide branch of arginine metabolism in depression: effect of venlafaxine. International Journal of Health Science. ,vol. 2, pp. 274- 281 ,(2009)
Varda H. Gilad, Jose M. Rabey, Ytzhak Kimiagar, Gad M. Gilad, The polyamine stress response: tissue-, endocrine-, and developmental-dependent regulation11Abbreviations: PA, polyamine; PSR, polyamine stress response; HPA, hypothalamic–pituitary–adrenocortical; ODC, ornithine decarboxylase. Biochemical Pharmacology. ,vol. 61, pp. 207- 213 ,(2001) , 10.1016/S0006-2952(00)00517-7
Salvatore Condello, Monica Currò, Nadia Ferlazzo, Daniela Caccamo, Joseph Satriano, Riccardo Ientile, Agmatine effects on mitochondrial membrane potential and NF-κB activation protect against rotenone-induced cell damage in human neuronal-like SH-SY5Y cells. Journal of Neurochemistry. ,vol. 116, pp. 67- 75 ,(2011) , 10.1111/J.1471-4159.2010.07085.X
Vivian Binder Neis, Luana Meller Manosso, Morgana Moretti, Andiara E Freitas, Juliana Daufenbach, Ana Lúcia S Rodrigues, None, Depressive-like behavior induced by tumor necrosis factor-α is abolished by agmatine administration. Behavioural Brain Research. ,vol. 261, pp. 336- 344 ,(2014) , 10.1016/J.BBR.2013.12.038
Serenay Elgün, Hakan Kumbasar, Increased serum arginase activity in depressed patients Progress in Neuro-Psychopharmacology and Biological Psychiatry. ,vol. 24, pp. 227- 232 ,(2000) , 10.1016/S0278-5846(99)00100-1
Serpil Canpolat, İsmet Kırpınar, Erdem Deveci, Hülya Aksoy, Zafer Bayraktutan, İbrahim Eren, Recep Demir, Salih Selek, Nazan Aydın, Relationship of Asymmetrical Dimethylarginine, Nitric Oxide, and Sustained Attention during Attack in Patients with Major Depressive Disorder The Scientific World Journal. ,vol. 2014, pp. 624395- 624395 ,(2014) , 10.1155/2014/624395
Laura Musazzi, Giorgio Racagni, Maurizio Popoli, Stress, glucocorticoids and glutamate release: Effects of antidepressant drugs Neurochemistry International. ,vol. 59, pp. 138- 149 ,(2011) , 10.1016/J.NEUINT.2011.05.002
Wei-zheng Zhang, David M Kaye, Simultaneous determination of arginine and seven metabolites in plasma by reversed-phase liquid chromatography with a time-controlled ortho-phthaldialdehyde precolumn derivatization. Analytical Biochemistry. ,vol. 326, pp. 87- 92 ,(2004) , 10.1016/J.AB.2003.11.006
Heinrich Wiesinger, Arginine metabolism and the synthesis of nitric oxide in the nervous system. Progress in Neurobiology. ,vol. 64, pp. 365- 391 ,(2001) , 10.1016/S0301-0082(00)00056-3
Mark A. McEvoy, Peter Schofield, Wayne Smith, Kingsley Agho, Arduino A Mangoni, Roy L Soiza, Roseanne Peel, Stephen Hancock, Brian Kelly, Kerry Inder, Ciriaco Carru, Angelo Zinellu, John Attia, Serum methylarginines and incident depression in a cohort of older adults. Journal of Affective Disorders. ,vol. 151, pp. 493- 499 ,(2013) , 10.1016/J.JAD.2013.06.033