Novel valve and process for interrupted continuous flow chromatography
作者： Anthony Joseph Escarcega , Saurabh Paresh Parikh , Kenneth U. Johnson , Asha Anil Oroskar , Anil Rajaram Oroskar
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摘要: A unique valve assembly for simulated bed moving chromatography employs a combination of pressure compatible sealable materials that permit minimal frictional interaction between parts, ensures alignment and provides method conducting SMB countercurrent on small scale, in which purity separation efficiency are enhanced. Machine designs disclosed embody the concepts. Finally, quick disconnect connector adaptor is provided mounting chromatographic columns an device. Demonstration this system fructose-glucose isomer with purity-recovery trade-off device also presented.
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