CHOLIC ACID DERIVATIVE, AND PREPARATION METHOD AND MEDICAL USE THEREOF
作者： Zhong Huijuan , Lv Aifeng , Li Chenghai , Bao Rudi
DOI:
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摘要: The present invention relates to a cholic acid derivative, and preparation method medical use thereof. In particular, the derivative with structure of formula (I), stereoisomer, or pharmaceutically acceptable salt series compounds can be used treat FXR mediated diseases, comprising cardiovascular disease, atherosclerosis, arteriosclerosis, hypercholesterolemia, hyperlipidemia chronic hepatitis liver gastrointestinal nephrosis, heart vascular metabolic cancer (for example colorectal cancer) neurological signs, such as strokes other wide range applications, are expected develop into new generation agonist.
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