Stabilized fibroblast growth factor composition
作者： Sandor Szabo , Yuen Shing , Moses Judah Folkman
DOI:
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摘要: Methods for stabilizing fibroblast growth factor (FGF) in heat, acid and/or proteolytic environments are provided. Such methods comprise combining or otherwise complexing FGF with a salt of sucrose octasulfate (SOS) and particular the aluminum (sucralfate) potassium salts thereof. The present invention also provides FGF-stable compositions comprising SOS FGF. can be used treatment FGF-responsive diseases including wounds ulcerative conditions gastrointestinal tract. various diagnostic protocols employing as well kits component Finally, purifying SOS.
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