Left ventricular geometry in obesity: Is it what we expect?

摘要: Obesity is characterized by the disproportionate growth of components body size, including adipose tissue and lean mass. Left ventricular (LV) hypertrophy often develops, due to coexistence hemodynamic (cardiac workload) non-hemodynamic (including composition activity visceral fat). While cardiomyocytes produced load, through sarcomeric replication, there a parallel non-muscular myocardial components, interstitial fat infiltration accumulation triglycerides in contractile elements, which are thought influence LV geometric pattern. Thus, pure intervention on load unlikely result effective reduction obese. We review pathophysiology prevalence obesity, with specific attention abnormalities relations size.