Individual Differences in the Amount and Timing of Salivary Melatonin Secretion

摘要: The aim of this study was to examine individual differences in a large sample complete melatonin profiles not suppressed by light and search for possible associations between the amount timing secretion multitude lifestyle variables. were derived from saliva samples collected every 30 minutes dim 85 healthy women men aged 18-45 years. There variability secreted with peak values ranging 2 84 pg/ml. onset ranged 18:13 00:26 hours. use hormonal birth control, reduced levels employment, smaller number days on fixed sleep schedule, increased day length lower weight associated an amplitude secretion. contact lenses, younger age, ratings mania paranoia longer duration An earlier occurrence wake time, more morningness absence bed partner. Lifestyle behavioral variables only able explain about 15% secretion, which is likely because substantial genetic influence