A Novel Oxytocin-Like and Vasotocin-Like Peptide in Human Plasma after Administration of Estrogen

作者: JANET A. AMICO , M. GORE ERVIN , ROSEMARY D. LEAKE , DELBERT A. FISHER , FRANCES M. FINN

DOI: 10.1210/JCEM-60-1-5

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摘要: Using three antisera to oxytocin (OT Pitt Ab-1, OT Ab-2, and TOR Ab), we found comparable levels of in response infant suckling during infusion synthetic OT, identical standard curves with biological standards OT. but not Ab-2 or Ab, measured increased estrogen. an arginine vasotocin RIA (TOR AVT increase immunoreactivity after estrogen treatment. Mean basal plasma men [0.75 ± 0.06 (±SEM) μU/ml] women (0.8 0.09 n]J/ ml) were lower than Ab-1 (1.7 μU/ml 1.7 0.07 women; P < 0.001). the given chronically 0.04 μU/ml) acutely (0.6 0.15 significantly different from levels. same samples 4.6 0.5 4.3 / μU/ml, respectively, both from...

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