作者: Satoshi Akagi , Hiromi Matsubara , Aiko Ogawa , Yusuke Kawai , Kenichi Hisamatsu
DOI: 10.1253/CIRCJ.71.559
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摘要: Background Most of the patients with pulmonary arterial hypertension (PAH) receiving intravenous epoprostenol have experienced catheter-related infections during long-term treatment. Catheter hub was reported to be most important source infections. To prevent infections, we introduced a closed system and compared incidence that in using non-closed system. Methods Results We evaluated results obtained on 24 occasions 20 PAH between June 1999 December 2005. On 11 occasions, used 13 cases classified infection into bloodstream (CRBSI) group or tunnel based pathway bacteria. The CRBSI rate 0.89 per 1,000 catheter days vs 0.10 group. Kaplan - Meier analysis showed risk significantly decreased None died as direct consequence study period. Conclusions successfully prevented by (Circ J 2007; 71: 559 564)