SKIN INFECTIONS AND ACUTE NEPHRITIS IN AMERICAN INDIAN CHILDREN

摘要: Serial observations were obtained over an 18-month period of 270 Indian children with pyoderma. Beta-hemolytic streptococci, predominantly group A, and coagulasepositive staphylococci recovered from the majority lesions (80% 70%, respectively), both on initial subsequent cultures. The predominant agglutination patterns streptococcal strains similar to those described in other studies superficial skin infections. Another pattern, 17/23/47, not previously observed be prevalent streptococci lesions, was identified a significant number In addition, hitherto undescribed association M-types, including type 41 new M-type, T-agglutination pattern 3/13/B3264 found. striking contrast strains, established "impetigo" Staph. aureus (type 71 or II strains) minority. Throat cultures pyoderma suggested limited relationship between infection colonization pharynx skin, while nasal more closely correlated possibly derived flora lesions. Titers ASO often elevated control values pyoderma, anti-DNAse B titers commonly increased. Group A isolated prior at time acute nephritis recognized included 12 (M T) classified by as 5/27/44, 11 4. role upper respiratory tract clarified these studies. Moreover, view frequency change shown serial this study, nephritogenic significance recognition must remain some doubt. Questions concerning pathogenesis endemic associated can probably most reliably answered frequent, prospective normal population occurrence