Tissue-type-plasminogen-activator-associated fibrinolysis in orthotopic liver transplantation.

摘要: Orthotopic liver transplantation is frequently associated with hemostatic disorders and a bleeding diathesis.1,2 Accelerated fibrinolysis has been recognized as an important component of the defect.1,2 The origin this fibrinolytic activity, however, still unclear. We investigated role tissue-type plasminogen activator (tPA), potent system, in increased activity during orthotopic transplantation.