The genetic and epigenetic landscape for CNS drug discovery targeting cross-diagnostic behavioral domains
作者： Annetrude (J.G.) de Mooij-van Malsen , Eneda Pjetri , Martien J. Kas
DOI: 10.1016/J.EJPHAR.2014.07.043
关键词:
摘要: Animal studies play a central role in the identification and testing of novel drugs for CNS disorders. In his longstanding career, Berend Olivier has significantly contributed to drug discovery by applying supporting views methodologies fields behavioral neuroscience, pharmacology, (epi-) genetics. Here we review put forward some these integrated approaches that have led productive collaboration new insights into genetic epigenetic regulation neurobehavioural traits related psychiatric
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