Modelling of the prebiotic synthesis of oligopeptides: silicate catalysts help to overcome the critical stage.

摘要: On the basis of experimental studies initial stages glycine oligomerization in aqueous suspension zeolite and kaolinite catalysts, a model is suggested for prebiotic synthesis oligopeptides from α-amino acids. The formation linear dipeptides by hydrolysis one amide bond cyclic piperazinedione intermediate (formed spontaneously) found to be critical stage reaction. This base catalyzed its rate increases when pH medium goes up. glycyl-glycine yield rises under effect hydroxyl anions generated different sources including insoluble silicates soluble sodium bicarbonate. During evolution capable cation-exchange can serve as local which dramatically accelerate ones. Oligopeptides higher molecular weight are then easily formed at neutral pH, even absence catalysts or energy (e.g. such light). described catalytic could occur proximity submarine hydrothermal vents.