Biomarker-driven targeted therapies for gastric/gastro-esophageal junction malignancies

作者: Salem Kim , Afsaneh Barzi , Lakshmi Rajdev

DOI: 10.1053/J.SEMINONCOL.2018.03.001

关键词:

摘要: Gastroesophageal malignancies often contain high amounts of genetic and molecular alterations that result in an aggressive disease capable rapidly metastasizing to distant organs early development drug resistance. Most patients the Western hemisphere present with locally advanced or metastatic is treated systemic chemotherapy used either neoadjuvant palliative setting, respectively. This article will review various recent advances targeted therapies for treatment gastric gastroesophageal cancer.

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