Fluorescence activated enrichment of CD146+ cells during expansion of human bone-marrow derived mesenchymal stromal cells augments proliferation and GAG/DNA content in chondrogenic media.
作者： Sebastien Hagmann , Sebastian Frank , Tobias Gotterbarm , Thomas Dreher , Volker Eckstein
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摘要: Background While numerous subpopulations of BM-MSCs have been identified, the relevance these findings regarding functional properties remains mostly unclear. With regards to attempts enhancing differentiation results by preselecting certain MSC subtypes, we evaluated efficiency CD146 purification during expansion, and whether measures enhanced results.
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