Attributing Hypodensities on CT to Angiographic Vasospasm Is Not Sensitive and Unreliable

作者: George M. Ibrahim , Stephan Weidauer , Hartmut Vatter , Andreas Raabe , R. Loch Macdonald

DOI: 10.1161/STROKEAHA.111.632745

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摘要: Background and Purpose—The presence of low-density areas on CT is used in clinical decision-making regarding treatment angiographic vasospasm as well research a surrogate marker for severity vasospasm. We assess the interobserver variability attributing hypodensities to vasospasm-related delayed ischemic neurological deficit. Methods—Three experienced reviewers, 2 neurosurgeons, neuroradiologist independently reviewed scans 413 patients enrolled Clazosentan Overcome Neurological iSChemia Infarction OccUrring after Subarachnoid hemorrhage (CONSCIOUS-1) trial, who universally underwent catheter angiography determine Interobserver was calculated using κ statistic χ2 test associations between dichotomized outcomes. Results—There considerable neurologica...

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