作者: Carlos Acevedo , Keryma Acevedo
DOI: 10.1016/B978-0-444-52899-5.00038-1
关键词:
摘要: Abstract Approximately 70% of patients with epilepsy achieve seizure freedom using antiepileptic drugs. Their cost has increased steadily in recent decades, restricting drug access for many developing countries. Implementation containment policies is crucial. One approach includes the use generic drugs, which are widely prescribed because their lower price. However, it must be considered that 80–125% range between pharmacokinetic parameters and innovative formulations wide, there risks breakthrough seizures side-effects when switching brand Sometimes this even performed without consent both patient physician. No state regarding generics available now, but specific recommendations from societies worldwide. Specific addressing these issues needed, medications a well-controlled considered. In addition, efforts directed to reduce treatment gap countries, comprising failure accurately diagnose, study, treat patients, further needed. Issues can approached through organized interventions such as national programs assuring universal at least older