Rethinking the composition of a rational antibiotic arsenal for the 21st century

摘要: The importance of the human microbiome in health may be single most valuable development our conception microbial world since Pasteur’s germ theory 1860s. Its implications for understanding and pathogenesis are profound. Coupled with revolution diagnostics that we now witnessing – a changes medicine from science symptoms to causes cannot continue develop antibiotics as have past 80 years. Instead, need usher new role treatment: away molecules target broad phylogenetic spectra towards targeted cripple pathogen while leaving rest largely intact.