Effect of aging and bolus variables on pharyngeal and upper esophageal sphincter motor function.

作者: R. Shaker , J. Ren , B. Podvrsan , W. J. Dodds , W. J. Hogan

DOI: 10.1152/AJPGI.1993.264.3.G427

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摘要: Effect of aging, bolus volume, temperature, and consistency on the pharyngeal peristalsis, as well effect aging upper esophageal sphincter (UES) resting pressure its response to distension by air balloon, were studied in 14 young 12 healthy elderly volunteers. In both age groups there was no significant volume or temperature amplitude, duration, velocity peristalsis. Compared with water swallows, mashed potato swallows resulted a increase amplitude duration hypopharyngeal peristaltic wave (P < 0.05). For hypopharynx significantly increased compared group 0.01). UES measured 43 +/- 5 (SE) mmHg less than that (71 8 mmHg; P Magnitude decrease because air, magnitude balloon distension, similar among elderly. 1) Contrary common expectations, parameters do not deteriorate their seventh eighth decade. 2) young, are This could be caused an adaptation outflow compromise. 3) Pharyngeal but velocity, modulated consistency. modulatory mechanism is preserved 4) Although decreased elderly, preserved.

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