Tumor genotype determines phenotype and disease-related outcomes in thyroid cancer: a study of 1510 patients.

作者: Linwah Yip , Marina N. Nikiforova , Jenny Y. Yoo , Kelly L. McCoy , Michael T. Stang

DOI: 10.1097/SLA.0000000000001420

关键词:

摘要: Objectives:To correlate thyroid cancer genotype with histology and outcomes.Background:The prognostic significance of molecular signature in (TC) is undefined but can potentially change surgical management.Methods:We reviewed a consecutive series 1510 patients who had initial thyro

参考文章(29)
Yuri E. Nikiforov, Sally E. Carty, Simon I. Chiosea, Christopher Coyne, Umamaheswar Duvvuri, Robert L. Ferris, William E. Gooding, Steven P. Hodak, Shane O. LeBeau, N. Paul Ohori, Raja R. Seethala, Mitchell E. Tublin, Linwah Yip, Marina N. Nikiforova, Highly accurate diagnosis of cancer in thyroid nodules with follicular neoplasm/suspicious for a follicular neoplasm cytology by ThyroSeq v2 next-generation sequencing assay. Cancer. ,vol. 120, pp. 3627- 3634 ,(2014) , 10.1002/CNCR.29038
David A. Kleiman, Matthew J. Sporn, Toni Beninato, Michael J. Crowley, Anvy Nguyen, Alessia Uccelli, Theresa Scognamiglio, Rasa Zarnegar, Thomas J. Fahey, Preoperative BRAF(V600E) mutation screening is unlikely to alter initial surgical treatment of patients with indeterminate thyroid nodules Cancer. ,vol. 119, pp. 1495- 1502 ,(2013) , 10.1002/CNCR.27888
Michaele J. Armstrong, Huaitao Yang, Linwah Yip, N. Paul Ohori, Kelly L. McCoy, Michael T. Stang, Steven P. Hodak, Marina N. Nikiforova, Sally E. Carty, Yuri E. Nikiforov, PAX8/PPARγ rearrangement in thyroid nodules predicts follicular-pattern carcinomas, in particular the encapsulated follicular variant of papillary carcinoma. Thyroid. ,vol. 24, pp. 1369- 1374 ,(2014) , 10.1089/THY.2014.0067
N. Paul Ohori, Rashi Singhal, Marina N. Nikiforova, Linwah Yip, Karen E. Schoedel, Christopher Coyne, Kelly L. McCoy, Shane O. LeBeau, Steven P. Hodak, Sally E. Carty, Yuri E. Nikiforov, BRAF mutation detection in indeterminate thyroid cytology specimens: underlying cytologic, molecular, and pathologic characteristics of papillary thyroid carcinoma. Cancer Cytopathology. ,vol. 121, pp. 197- 205 ,(2013) , 10.1002/CNCY.21229
Nishant Agrawal, Rehan Akbani, B Arman Aksoy, Adrian Ally, Harindra Arachchi, Sylvia L Asa, J Todd Auman, Miruna Balasundaram, Saianand Balu, Stephen B Baylin, Madhusmita Behera, Brady Bernard, Rameen Beroukhim, Justin A Bishop, Aaron D Black, Tom Bodenheimer, Lori Boice, Moiz S Bootwalla, Jay Bowen, Reanne Bowlby, Christopher A Bristow, Robin Brookens, Denise Brooks, Robert Bryant, Elizabeth Buda, Yaron SN Butterfield, Tobias Carling, Rebecca Carlsen, Scott L Carter, Sally E Carty, Timothy A Chan, Amy Y Chen, Andrew D Cherniack, Dorothy Cheung, Lynda Chin, Juok Cho, Andy Chu, Eric Chuah, Kristian Cibulskis, Giovanni Ciriello, Amanda Clarke, Gary L Clayman, Leslie Cope, John A Copland, Kyle Covington, Ludmila Danilova, Tanja Davidsen, John A Demchok, Daniel DiCara, Noreen Dhalla, Rajiv Dhir, Sheliann S Dookran, Gideon Dresdner, Jonathan Eldridge, Greg Eley, Adel K El-Naggar, Stephanie Eng, James A Fagin, Timothy Fennell, Robert L Ferris, Sheila Fisher, Scott Frazer, Jessica Frick, Stacey B Gabriel, Ian Ganly, Jianjiong Gao, Levi A Garraway, Julie M Gastier-Foster, Gad Getz, Nils Gehlenborg, Ronald Ghossein, Richard A Gibbs, Thomas J Giordano, Karen Gomez-Hernandez, Jonna Grimsby, Benjamin Gross, Ranabir Guin, Angela Hadjipanayis, Hollie A Harper, D Neil Hayes, David I Heiman, James G Herman, Katherine A Hoadley, Matan Hofree, Robert A Holt, Alan P Hoyle, Franklin W Huang, Mei Huang, Carolyn M Hutter, Trey Ideker, Lisa Iype, Anders Jacobsen, Stuart R Jefferys, Corbin D Jones, Steven JM Jones, Katayoon Kasaian, Electron Kebebew, Fadlo R Khuri, Jaegil Kim, Roger Kramer, Richard Kreisberg, Raju Kucherlapati, David J Kwiatkowski, Marc Ladanyi, Phillip H Lai, Peter W Laird, Eric Lander, Michael S Lawrence, Darlene Lee, Eunjung Lee, Semin Lee, William Lee, Kristen M Leraas, Tara M Lichtenberg, Lee Lichtenstein, Pei Lin, Shiyun Ling, Jinze Liu, Wenbin Liu, Yingchun Liu, Virginia A LiVolsi, Yiling Lu, Yussanne Ma, Harshad S Mahadeshwar, Marco A Marra, Michael Mayo, David G McFadden, Shaowu Meng, Matthew Meyerson, Piotr A Mieczkowski, Michael Miller, Gordon Mills, Richard A Moore, Lisle E Mose, Andrew J Mungall, Bradley A Murray, Yuri E Nikiforov, Michael S Noble, Akinyemi I Ojesina, Taofeek K Owonikoko, Bradley A Ozenberger, Angeliki Pantazi, Michael Parfenov, Peter J Park, Joel S Parker, Evan O Paull, Chandra Sekhar Pedamallu, Charles M Perou, Jan F Prins, Alexei Protopopov, None, Integrated Genomic Characterization of Papillary Thyroid Carcinoma Cell. ,vol. 159, pp. 676- 690 ,(2014) , 10.1016/J.CELL.2014.09.050
Zubair W. Baloch, Virginia A. LiVolsi, Syl L. Asa, Juan Rosai, Maria J. Merino, Gregory Randolph, Philippe Vielh, Richard M. DeMay, Mary K. Sidawy, William J. Frable, Diagnostic terminology and morphologic criteria for cytologic diagnosis of thyroid lesions: a synopsis of the National Cancer Institute Thyroid Fine-Needle Aspiration State of the Science Conference. Diagnostic Cytopathology. ,vol. 36, pp. 425- 437 ,(2008) , 10.1002/DC.20830
Kathleen C. Lee, Carol Li, Eric B. Schneider, Yongchun Wang, Helina Somervell, Matthew Krafft, Christopher B. Umbricht, Martha A. Zeiger, Is BRAF mutation associated with lymph node metastasis in patients with papillary thyroid cancer Surgery. ,vol. 152, pp. 977- 983 ,(2012) , 10.1016/J.SURG.2012.08.019
Linwah Yip, Marina N. Nikiforova, Sally E. Carty, John H. Yim, Michael T. Stang, Mitchell J. Tublin, Shane O. LeBeau, Steven P. Hodak, Jennifer B. Ogilvie, Yuri E. Nikiforov, Optimizing surgical treatment of papillary thyroid carcinoma associated with BRAF mutation Surgery. ,vol. 146, pp. 1215- 1223 ,(2009) , 10.1016/J.SURG.2009.09.011
Mingzhao Xing, Bryan R Haugen, Martin Schlumberger, Progress in molecular-based management of differentiated thyroid cancer The Lancet. ,vol. 381, pp. 1058- 1069 ,(2013) , 10.1016/S0140-6736(13)60109-9
Yuri E. Nikiforov, N. Paul Ohori, Steven P. Hodak, Sally E. Carty, Shane O. LeBeau, Robert L. Ferris, Linwah Yip, Raja R. Seethala, Mitchell E. Tublin, Michael T. Stang, Christopher Coyne, Jonas T. Johnson, Andrew F. Stewart, Marina N. Nikiforova, Impact of Mutational Testing on the Diagnosis and Management of Patients with Cytologically Indeterminate Thyroid Nodules: A Prospective Analysis of 1056 FNA Samples The Journal of Clinical Endocrinology & Metabolism. ,vol. 96, pp. 3390- 3397 ,(2011) , 10.1210/JC.2011-1469