Metabolic Syndrome and cognitive decline in the elderly: A systematic review.

摘要: Background Metabolic Syndrome (MetS) refers to a cluster of metabolic disturbances which is associated with increased risk for vascular and degenerative conditions in general population. Although the relationship between factors dementia undisputable, additional hazard cognitive decline older population concurrent disorders still waits be demonstrated. The present review aims analyze data on MetS elderly persons. Methods Database searches were performed Medline, ISI PsycINFO articles assessing performances subjects MetS. Results Of total 505 studies, 25 selected review. Risk selection biases was identified all studies. followed recognized diagnostic recommendations MetS, minor criteria modifications detected most them. Hyperglycemia consistently impaired individuals, but role onset showed heterogeneous results. Discussion Current available literature concerning impact cognition inconclusive based inconsistent evidence. Differential effects individual components age sample may have accounted divergent findings among articles, larger higher quality studies this field are needed.