Total synthesis of cruciferane via epoxidation/tandem cyclization sequence
作者： Suman Kr Ghosh , Rajagopal Nagarajan
DOI: 10.1039/C4RA10309B
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摘要: The total synthesis of alkaloid cruciferane is performed in three steps with an overall yield 60.3%. key step involves the situ epoxidation indole followed by tandem Cyclization via epoxide ring opening to furnish 3-hydroxypyrroloindoline skeleton. This methodology gave a economical and protecting group free cruciferane.
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