Cost effectiveness of ramipril in patients at high risk for cardiovascular events : economic evaluation of the HOPE (Heart Outcomes Prevention Evaluation) study for Germany from the Statutory Health Insurance perspective.

作者: Peter K. Schädlich , Josef Georg Brecht , Badrudin Rangoonwala , Eduard Huppertz

DOI: 10.2165/00019053-200422150-00001

关键词:

摘要: Background: In the HOPE (Heart Outcomes Prevention Evaluation) trial, ramipril (compared with placebo) significantly reduced cardiovascular death and all-cause mortality as well incidence of costly events, such myocardial infarction, revascularisation, stroke, cardiac arrest, hospitalisation due to heart failure worsening angina pectoris, new-onset diabetes mellitus microvascular diabetic complications.

参考文章(51)
David Wood, Guy De Backer, Ole Faergeman, Ian Graham, Giuseppe Mancia, Kalevi Pyörälä, Prevention of coronary heart disease in clinical practice: recommendations of the Second Joint Task Force of European and other Societies on Coronary Prevention. Atherosclerosis. ,vol. 140, pp. 199- 270 ,(1998) , 10.1016/S0021-9150(98)90209-X
J.Robert Beck, Stephen G. Pauker, Jonathan E. Gottlieb, Karen Klein, Jerome P. Kassirer, A convenient approximation of life expectancy (the “DEALE”): II. Use in medical decision-making The American Journal of Medicine. ,vol. 73, pp. 889- 897 ,(1982) , 10.1016/0002-9343(82)90787-2
Ronald L. Wasserstein, Monte Carlo: Concepts, Algorithms, and Applications Technometrics. ,vol. 39, pp. 338- 338 ,(1997) , 10.1080/00401706.1997.10485133
Salim Yusuf, Hertzel Gerstein, Byron Hoogwerf, Janice Pogue, Jackie Bosch, Bruce HR Wolffenbuttel, Bernard Zinman, HOPE Study Investigators, HOPE Study Investigators, None, Ramipril and the Development of Diabetes JAMA. ,vol. 286, pp. 1882- 1885 ,(2001) , 10.1001/JAMA.286.15.1882