First case of transformation for breast fibroadenoma to high-grade malignant phyllodes tumor in an in vitro fertilization patient: misdiagnosis of recurrence, treatment and review of the literature.

摘要: INTRODUCTION : Cystosarcoma phyllodesareveryraretumorsandmaybediffi- culttodiagnoseclinically. BACKGROUND: Fibroadenomas have long been considered benign hyperplastic lesions ratherthantrueneoplasticprocesses.However, previous clonality studies shown differing results. AIM to assess diagnostic and treatment op - tions for phyllodes tumor. MATERIALS AND METHODS: A 41-year-old female patient undergoing assisted fertilization treatment. The underwent fine needle aspiration biopsy that confirmed fibroadenoma before the IVF attempt. At 17 weeks of gesta tion, due an increase in volume fi- broadenoma, excisional was per former showed a malignant tu mor. Then she quadrantectomy chemiotherapy After 1 year there recur rence tumors mastectomy chemotherapy. RESULTS: Fibroadenoma trans formed into high-grade cystosarcoma after ovarian stimulation, relapsed one it not immediately diagnosed. pa tient DISCUSSION: is difficult diagnose determine tehe frequency right such rare cancer, so important report any case literature. CONCLUSIONS: We recommend remove attempting risk transformation.