Andrographolide inhibits TNFα-induced ICAM-1 expression via suppression of NADPH oxidase activation and induction of HO-1 and GCLM expression through the PI3K/Akt/Nrf2 and PI3K/Akt/AP-1 pathways in human endothelial cells
作者： Chia-Yang Lu , Ya-Chen Yang , Chien-Chun Li , Kai-Li Liu , Chong-Kuei Lii
DOI: 10.1016/J.BCP.2014.06.024
关键词:
摘要: … GCLM in controlling the GSH level by using Gclm −/− mice. In addition, it has been shown that mice deficient in the Gclm … up-regulated GCLM expression and that knockdown of GCLM …
sci-hub.se 参考文章(62)
Bernhard Schieffer, Maren Luchtefeld, Sabine Braun, Andres Hilfiker, Denise Hilfiker-Kleiner, Helmut Drexler, Role of NAD(P)H Oxidase in Angiotensin II–Induced JAK/STAT Signaling and Cytokine Induction Circulation Research. ,vol. 87, pp. 1195- 1201 ,(2000) , 10.1161/01.RES.87.12.1195
Hua Cai, David G. Harrison, Endothelial Dysfunction in Cardiovascular Diseases: The Role of Oxidant Stress Circulation Research. ,vol. 87, pp. 840- 844 ,(2000) , 10.1161/01.RES.87.10.840
Anthony Y. H. Woo, Mary M. Y. Waye, Stephen K. W. Tsui, Sandy T. W. Yeung, Christopher H. K. Cheng, Andrographolide Up-Regulates Cellular-Reduced Glutathione Level and Protects Cardiomyocytes against Hypoxia/Reoxygenation Injury Journal of Pharmacology and Experimental Therapeutics. ,vol. 325, pp. 226- 235 ,(2008) , 10.1124/JPET.107.133918
Jin Ding, Beifang Ning, Yi Huang, Dongyun Zhang, Jingxia Li, Chang-Yan Chen, Chuanshu Huang, PI3K/Akt/JNK/c-Jun signaling pathway is a mediator for arsenite-induced cyclin D1 expression and cell growth in human bronchial epithelial cells. Current Cancer Drug Targets. ,vol. 9, pp. 500- 509 ,(2009) , 10.2174/156800909788486740
Dale A. Dickinson, Karen E. Iles, Hongqiao Zhang, Volker Blank, Henry Jay Forman, Curcumin alters EpRE and AP-1 binding complexes and elevates glutamate-cysteine ligase gene expression The FASEB Journal. ,vol. 17, pp. 473- 475 ,(2003) , 10.1096/FJ.02-0566FJE
Sanchayita Mitra, Edward Abraham, Participation of superoxide in neutrophil activation and cytokine production. Biochimica et Biophysica Acta. ,vol. 1762, pp. 732- 741 ,(2006) , 10.1016/J.BBADIS.2006.06.011
Shelly C. Lu, Regulation of glutathione synthesis Molecular Aspects of Medicine. ,vol. 30, pp. 42- 59 ,(2009) , 10.1016/J.MAM.2008.05.005
Elisa Giannoni, Francesca Buricchi, Giovanni Raugei, Giampietro Ramponi, Paola Chiarugi, Intracellular Reactive Oxygen Species Activate Src Tyrosine Kinase during Cell Adhesion and Anchorage-Dependent Cell Growth Molecular and Cellular Biology. ,vol. 25, pp. 6391- 6403 ,(2005) , 10.1128/MCB.25.15.6391-6403.2005
Wen-Wan Chao, Bi-Fong Lin, Isolation and identification of bioactive compounds in Andrographis paniculata ( Chuanxinlian ) Chinese Medicine. ,vol. 5, pp. 17- 17 ,(2010) , 10.1186/1749-8546-5-17
Christopher G. Kevil, Rakesh P. Patel, Daniel C. Bullard, Essential role of ICAM-1 in mediating monocyte adhesion to aortic endothelial cells. American Journal of Physiology-cell Physiology. ,vol. 281, ,(2001) , 10.1152/AJPCELL.2001.281.5.C1442