Molecular diagnosis and typing of lung cancer variants
作者： David N. Hayes , Charles M. Perou , Philip Bernard
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摘要: Compositions and methods useful in determining the major morphological types of lung cancer are provided. The include detecting expression at least one gene or biomarker a sample. is indicative tumor subtype. compositions subsets genes that monitored for expression. capable distinguishing between normal parenchyma cancer. somatic mutation data developing complete classification prognostic predictive therapeutic response. suited analysis paraffin-embedded tissues. Methods invention means monitoring including PCR antibody-based detection. biomarkers and/or proteins selectively expressed high low level certain subtypes. Biomarker can be assessed protein nucleic acid level.
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