Effect of frailty on short- and mid-term outcomes in vascular surgical patients

摘要: Background Frailty is a multidimensional vulnerability resulting from age-associated decline. The impact of frailty on outcomes was assessed in cohort vascular surgical patients. Methods The study included patients aged over 65 years with length hospital stay (LOS) greater than 2 days, who were admitted to tertiary unit single calendar year. Demographics, mode admission, diagnosis, mortality, LOS and discharge destination recorded, as well variety frailty-specific characteristics. LOS, destination, survival readmission rate using multivariable regression techniques. ability the models predict these also assessed. Results In total, 413 median age 77 years followed for 18 (range 12–24) months. in-hospital, 3- 12-month mortality rates 3·6, 8·5 13·8 per cent respectively. Receiver operating characteristic (ROC) curve analysis revealed that frailty-based excellent predictors (area under ROC (AUC) = 0·81), prolonged (AUC = 0·79) care institution (AUC = 0·84). A simple additive score six key features retained strong predictive power (AUC = 0·83), (AUC = 0·78) (AUC = 0·74). This strongly associated (P < 0·001). Conclusion Frailty surgery predicts multiplicity poorer outcomes. Optimal management should include identification at-risk treatment modifiable risk factors.