作者: Biao He
DOI:
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摘要: The present invention provides safe, stable, efficacious, and cost-effective vaccines based on viral expression vectors that include a parainfluenza virus 5 (PIV5) genome including heterologous nucleotide sequence expressing polypeptide. In some embodiments, the is inserted closer to leader than between hemagglutinin-neuroaminidase (HN) gene large RNA polymerase protein (L) of PIV5 genome. small hydrophobic (SH) PIV