Genetic liability to osteoarthritis may be greater in women than men.

作者: J. Kaprio , U. M Kujala , L. Peltonen , M. Koskenvuo

DOI: 10.1136/BMJ.313.7051.232

关键词:

摘要: EDITOR,—Tim D Spector and colleagues report a study of genetic influences on osteoarthritis in monozygotic dizygotic female twins.1 They conclude that their results show clear effect for radiographic the hand knee women (ranging from 39% to 65%) independent known environmental or demographic confounders. In his commentary paper John Hopper states these figures must be considered an upper bound influence.1 In questionnaire sent Finnish twin cohort …

参考文章(2)
Sarna S, Koskenvuo M, Kaprio J, Rantasalo I, The Finnish Twin Registry: formation and compilation, questionnaire study, zygosity determination procedures, and research program. Progress in Clinical and Biological Research. pp. 179- ,(1978)
T. D Spector, F. Cicuttini, J. Baker, J. Loughlin, D. Hart, Genetic influences on osteoarthritis in women: a twin study BMJ. ,vol. 312, pp. 940- 943 ,(1996) , 10.1136/BMJ.312.7036.940