摘要: Breast cancer is a complex disease caused by the progressive accumulation of multiple gene mutations combined with epigenetic dysregulation critical genes and protein pathways. There substantial interindividual variability in both age at diagnosis phenotypic expression disease. With an estimated 1,152,161 new breast cases diagnosed worldwide per year, cancer-control efforts post-genome era should be focused population individual levels to develop novel risk assessment treatment strategies that will further reduce morbidity mortality associated
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