Comparative Biological Activities of Five Thai Medicinal Plants Called Hua-Khao-Yen
作者： Arunporn Itharat
DOI:
关键词:
摘要: Plants named ‘Hua-Khao-Yen’ are common ingredients in traditional cancer remedies Thailand and best-selling medicinal plants drugstores. From the selective interview found that Hua-Khao-Yen was to comprise at least five species such as Dioscorea membranacea Pierre (Dioscoreaceae) (DM), D. burmanica Prain ex Burkill (DB), Smilax corbularia Kunth (Smilacaceae) (SC), S. glabra Roxb. (SG), or Pygmeopremna herbacea et (Verbenaceae)(PM). Three vitro bioassay were used compare activities of these cytotoxic , antioxidant antimicrobial activities.The extract procedures similar those practiced by Thai doctors (water ethanolic extraction). The SRB assay test cytotoxicity against two types human liver cell line (HepG2). lipid peroxidation liposomes for activity 5 plant extracts. Disc diffusion method activity. results extracts DB showed highest Hela (IC50=28.060±6.338 μg/ml) DM HepG2 (IC50=18.539±2.371 μg/ml). water no line. rhizome (EC50= 8.09 also with aureus B.subtilis E.floccosum
参考文章(5)
Arunporn Itharat, Peter J Houghton, E Eno-Amooquaye, P.J Burke, Julia H Sampson, Amala Raman, In vitro cytotoxic activity of Thai medicinal plants used traditionally to treat cancer Journal of Ethnopharmacology. ,vol. 90, pp. 33- 38 ,(2004) , 10.1016/J.JEP.2003.09.014
Satyajit D. Sarker, Lutfun Nahar, Yashodharan Kumarasamy, Microtitre plate-based antibacterial assay incorporating resazurin as an indicator of cell growth, and its application in the in vitro antibacterial screening of phytochemicals. Methods. ,vol. 42, pp. 321- 324 ,(2007) , 10.1016/J.YMETH.2007.01.006
Mitsuru Uchiyama, Midori Mihara, Determination of malonaldehyde precursor in tissues by thiobarbituric acid test Analytical Biochemistry. ,vol. 86, pp. 271- 278 ,(1978) , 10.1016/0003-2697(78)90342-1
P. Skehan, R. Storeng, D. Scudiero, A. Monks, J. McMahon, D. Vistica, J. T. Warren, H. Bokesch, S. Kenney, M. R. Boyd, New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening Journal of the National Cancer Institute. ,vol. 82, pp. 1107- 1112 ,(1990) , 10.1093/JNCI/82.13.1107
JM Pezzuto, M Suffness, Assays related to cancer drug discovery ,(1999)