Distinct E-cadherin-based complexes regulate cell behaviour through miRNA processing or Src and p120 catenin activity

作者: Antonis Kourtidis , Siu P. Ngok , Pamela Pulimeno , Ryan W. Feathers , Lomeli R. Carpio

DOI: 10.1038/NCB3227

关键词:

摘要: Anastasiadis and colleagues report the presence of two spatially functionally distinct E-cadherin-based junctional complexes, which influence cell behaviour either by regulating miRNA processing or promoting p120 catenin Src signalling.

参考文章(59)
Alpha S. Yap, Carien M. Niessen, Barry M. Gumbiner, The Juxtamembrane Region of the Cadherin Cytoplasmic Tail Supports Lateral Clustering, Adhesive Strengthening, and Interaction with p120ctn Journal of Cell Biology. ,vol. 141, pp. 779- 789 ,(1998) , 10.1083/JCB.141.3.779
Molly A. Thoreson, Panos Z. Anastasiadis, Juliet M. Daniel, Reneé C. Ireton, Margaret J. Wheelock, Keith R. Johnson, Diana K. Hummingbird, Albert B. Reynolds, Selective Uncoupling of P120 ctn from E-Cadherin Disrupts Strong Adhesion Journal of Cell Biology. ,vol. 148, pp. 189- 202 ,(2000) , 10.1083/JCB.148.1.189
Li-Wei Ma, Zeng-Tong Zhou, Qing-Bo He, Wei-Wen Jiang, Phosphorylated p120-catenin expression has predictive value for oral cancer progression Journal of Clinical Pathology. ,vol. 65, pp. 315- 319 ,(2012) , 10.1136/JCLINPATH-2011-200516
Serge Paschoud, Lionel Jond, Diego Guerrera, Sandra Citi, PLEKHA7 modulates epithelial tight junction barrier function. Tissue barriers. ,vol. 2, ,(2014) , 10.4161/TISB.28755
Yoontae Lee, Chiyoung Ahn, Jinju Han, Hyounjeong Choi, Jaekwang Kim, Jeongbin Yim, Junho Lee, Patrick Provost, Olof Rådmark, Sunyoung Kim, V. Narry Kim, The nuclear RNase III Drosha initiates microRNA processing Nature. ,vol. 425, pp. 415- 419 ,(2003) , 10.1038/NATURE01957
Fei-Fei Lan, Hua Wang, Yang-Chao Chen, Chu-Yan Chan, Samuel S. Ng, Kui Li, Dan Xie, Ming-Liang He, Marie C. Lin, Hsiang-Fu Kung, Hsa-let-7g inhibits proliferation of hepatocellular carcinoma cells by downregulation of c-Myc and upregulation of p16INK4A International Journal of Cancer. ,vol. 128, pp. 319- 331 ,(2011) , 10.1002/IJC.25336
Deborah Silvera, Rezina Arju, Farbod Darvishian, Paul H. Levine, Ladan Zolfaghari, Judith Goldberg, Tsivia Hochman, Silvia C. Formenti, Robert J. Schneider, Essential role for eIF4GI overexpression in the pathogenesis of inflammatory breast cancer Nature Cell Biology. ,vol. 11, pp. 903- 908 ,(2009) , 10.1038/NCB1900
J Buechner, E Tømte, B H Haug, J R Henriksen, C Løkke, T Flægstad, C Einvik, Tumour-suppressor microRNAs let-7 and mir-101 target the proto-oncogene MYCN and inhibit cell proliferation in MYCN -amplified neuroblastoma British Journal of Cancer. ,vol. 105, pp. 296- 303 ,(2011) , 10.1038/BJC.2011.220
Wenxiang Meng, Yoshimi Mushika, Tetsuo Ichii, Masatoshi Takeichi, Anchorage of Microtubule Minus Ends to Adherens Junctions Regulates Epithelial Cell-Cell Contacts Cell. ,vol. 135, pp. 948- 959 ,(2008) , 10.1016/J.CELL.2008.09.040