The Drosophila larval visual system: high-resolution analysis of a simple visual neuropil

摘要: The task of the visual system is to translate light into neuronal encoded information. This translation photons signals achieved by photoreceptor neurons (PRs), specialized sensory neurons, located in eye. Upon perception PRs will send a signal target which represent first station processing. Increasing complexity processing stems from number distinct PR subtypes and their various types that are contacted. fruit fly larva represents simple (larval optic neuropil, LON) consists 12 falling two classes: blue-senstive expressing Rhodopsin 5 (Rh5) green-sensitive 6 (Rh6). These afferents contact small including lobe pioneers (OLPs) lateral clock (LNs). We combine use genetic markers label both distinct, identifiable sets with serial EM reconstruction generate high-resolution map larval neuropil. find neuropil shows clear bipartite organization consisting one domain innervated devoid axons. topology projections, particular relationship between Rh5 Rh6 afferents, maintained nerve entering brain axon terminals. can be subdivided according neurotransmitter or neuropeptide they as well location within brain. further track through development instar its adult accessory medulla.