Identification of heptanal and nonanal in bronchoalveolar lavage from rats exposed to low levels of ozone
作者： Rafael Cueto , Giuseppe L. Squadrito , Eliezer Bermudez , William A. Pryor
DOI: 10.1016/0006-291X(92)92359-6
关键词:
摘要: Heptanal and nonanal are identified from in vitro studies as potential biomarkers of exposure to ozone, the former resulting ozonation palmitoleic acid latter oleic acid. An analytical method is developed based on derivatization using O-pentafluorobenzylhydroxylamine HCl gas chromatography. These molecules also present lung lavage Sprague-Dawley rats exposed 1.3 ppm ozone for 10 hr. results suggest aldehydes may be useful dosimeters indicate that unsaturated fatty acids lining fluid layer undergo vivo.
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