Worldwide thoracic organ transplantation: a report from the UNOS/ISHLT International Registry for Thoracic Organ Transplantation.

摘要: 1. The number of heart transplant operations performed in the US decreased by 52 procedures between 1996 (2,344) and 1997 (2,292). lung transplants increased 118 (928). 2. most frequently reported indication for transplantation was coronary artery disease (44.9%). For other thoracic transplants, indications included cystic fibrosis (36.8%) double-lung, emphysema/COPD (53.8%) single-lung congenital (33.9%) heart-lung transplants. diagnoses outside cardiomyopathy (50.4%) heart, (31.3%) idiopathic pulmonary (32.4%) primary hypertension (23.3%) 3. recipients were predominately male (77.4%), over age 50 (55.9%) white (82.1%). In contrast, predominantly female (51.9%), ages 35-64 (73.4%) (89.5%). No meaningful variance from recipient demographic profile noted non-US during same time period. 4. Mean ischemic showed minimal change hearts (2 minutes), a sharp increase heart-lungs (29.5 minutes) decrease lungs (11 1997-1998. 5. one-year survival rates 83.2% 75.7% 34.1% 1997. Five-year 66% 46.4% 1993. 6. Long-term patient were: 29.5% at 14 years 19.4% 9 26.2% 11 recipients. 7. important risk factor mortality one month, year conditionally 5 after receipt previous transplant. Significant short-term factors time. Substantial long-term older donor race. 8. having significant impact on all points related to either patient's medical condition (e.g.x, ICU prior transplant, requiring mechanical ventilation) or diagnosis. 9. Mechanical ventilation had largest mortality. 10. recipients, major cause rehospitalization first infection alone.