摘要: The tumour necrosis factor (TNF) family is intimately connected to the regulation of cellular pathways. A PRoliferation-Inducing Ligand (APRIL) a rather new member that family, named for its capacity stimulate proliferation cells in vitro. Subsequent publications also called this ligand TRDL-1 or TALL-2, respectively. APRIL and B-lymphocyte stimulator (BLyS; termed BAFF, TALL-1, THANK, zTNF4) form subfamily TNF-like ligands are expressed haematopoietic cells. Both can bind two members TNF receptor namely transmembrane activator calcium modulator cyclophilin interactor (TACI), as well B-cell maturation antigen (BCMA). BLyS has recently been subject several reviews (for an extensive review, see Mackay et al.). present review will thus focus on APRIL, discuss only briefly sake clarity.
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Minhong Yan, Hua Wang, Betty Chan, Meron Roose-Girma, Sharon Erickson, Thad Baker, Daniel Tumas, Iqbal S. Grewal, Vishva M. Dixit, Activation and accumulation of B cells in TACI-deficient mice Nature Immunology. ,vol. 2, pp. 638- 643 ,(2001) , 10.1038/89790
Olivier Lantz, Isabelle Grandjean, Polly Matzinger, James P. Di Santo, Gamma chain required for naïve CD4+ T cell survival but not for antigen proliferation. Nature Immunology. ,vol. 1, pp. 54- 58 ,(2000) , 10.1038/76917
Richard M Siegel, Michael J Lenardo, None, To B or not to B: TNF family signaling in lymphocytes Nature Immunology. ,vol. 2, pp. 577- 578 ,(2001) , 10.1038/89715
Jason G. Cyster, B cells on the front line. Nature Immunology. ,vol. 1, pp. 9- 10 ,(2000) , 10.1038/76859
Gang Yu, Tom Boone, John Delaney, Nessa Hawkins, Michael Kelley, Meena Ramakrishnan, Susan McCabe, Wan-rong Qiu, Masayo Kornuc, Xing-Zhong Xia, Jane Guo, Marina Stolina, William J. Boyle, Ildiko Sarosi, Hailing Hsu, Giorgio Senaldi, Lars E. Theill, APRIL and TALL-I and receptors BCMA and TACI: system for regulating humoral immunity. Nature Immunology. ,vol. 1, pp. 252- 256 ,(2000) , 10.1038/79802
Jane A. Gross, Janet Johnston, Sherri Mudri, Rachel Enselman, Stacey R. Dillon, Karen Madden, Wenfeng Xu, Julia Parrish-Novak, Don Foster, Cathy Lofton-Day, Margaret Moore, Alisa Littau, Angelika Grossman, Harald Haugen, Kevin Foley, Hal Blumberg, Kim Harrison, Wayne Kindsvogel, Christopher H. Clegg, TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease Nature. ,vol. 404, pp. 995- 999 ,(2000) , 10.1038/35010115
Viktor Roschke, Svetlana Sosnovtseva, Christopher D. Ward, June S. Hong, Rodger Smith, Vivian Albert, William Stohl, Kevin P. Baker, Stephen Ullrich, Bernardetta Nardelli, David M. Hilbert, Thi-Sau Migone, BLyS and APRIL form biologically active heterotrimers that are expressed in patients with systemic immune-based rheumatic diseases. Journal of Immunology. ,vol. 169, pp. 4314- 4321 ,(2002) , 10.4049/JIMMUNOL.169.8.4314
B Pradet‐Balade, JP Medema, M Lopez‐Fraga, JC Lozano, GM Kolfschoten, A Picard, C Martínez‐A, JA Garcia‐Sanz, M Hahne, An endogenous hybrid mRNA encodes TWE-PRIL, a functional cell surface TWEAK-APRIL fusion protein The EMBO Journal. ,vol. 21, pp. 5711- 5720 ,(2002) , 10.1093/EMBOJ/CDF565
David J. Miller, Keith D. Hanson, Julie A. Carman, Colleen E. Hayes, A single autosomal gene defect severely limits IgG but not IgM responses in B lymphocyte‐deficient A/WySnJ mice European Journal of Immunology. ,vol. 22, pp. 373- 379 ,(1992) , 10.1002/EJI.1830220213
Andrew Craxton, Dario Magaletti, Elizabeth J. Ryan, Edward A. Clark, Macrophage- and dendritic cell—dependent regulation of human B-cell proliferation requires the TNF family ligand BAFF Blood. ,vol. 101, pp. 4464- 4471 ,(2003) , 10.1182/BLOOD-2002-10-3123