Compositions and methods for modulating metabolism
作者： Jorge Plutzky , James Elliott Bradner , Jonathan Brown
DOI:
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摘要: The invention provides compositions comprising an effective amount of agent that inhibits a BET protein (e.g., Brd2, Brd3, Brd4), and methods using such for treating or preventing metabolic syndrome, obesity, type II diabetes, insulin resistance, related disorders characterized by undesirable alterations in metabolism fat accumulation.
google.de 参考文章(20)
Amit Mukharya, Abhaykumar Chandak, Anandi Krishnan, Sustained release matrix pharmaceutical composition ,(2007)
D. M. Weir, Handbook of experimental immunology ,(1967)
Alfonso R. Gennaro, Remington: The Science and Practice of Pharmacy ,(2003)
James Swarbrick, Encyclopedia of Pharmaceutical Technology ,(2006)
Shelby L. Berger, Alan R. Kimmel, Guide to molecular cloning techniques. Harcourt Brace Jovanovich Inc.,San Diego, CA. ,vol. 152, ,(1987)
Barbara Staehelin, Herman Kempen, Daniel Bellus, Thienotriazolodiazepine derivatives active on apo a ,(2009)
Peter G. M. Wuts, Theodora W. Greene, Protective groups in organic synthesis ,(1981)
Li-Xun Zhao, Arnold Lippa, Jing Wei, Jian-Dong Jiang, Wei-Jia Kong, Dan-Qing Song, Methods and compositions for the treatment of metabolic syndrome ,(2007)
James McSwiggen, Kenneth G. Draper, Dan T. Stinchcomb, Ribozyme treatment of diseases or conditions related to levels of NF-kappaB ,(1996)
Theresa M. Allen, Darrin D. Stuart, Liposome-entrapped polynucleotide composition and method ,(1998)