Melanoma differentiation associated gene - 5 and promoter and uses thereof
作者： Rahul V. Gopalkrishnan , Paul B. Fisher , Dong-Chul Kang
DOI:
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摘要: The invention provides for an isolated nucleic acid encoding Mda-5 (melanoma differentiation associated gene-5) and polypeptide. further a vector comprising the Mda-5, as well host cell vector. antibody which specifically binds to method determining whether compound is inducer of gene expression assays determine modifies enzymatic activity
lens.org 参考文章(80)
David Rank, Wensheng Chen, Sharron Penn, David Hanzel, Human genome-derived single exon nucleic acid probes useful for gene expression analysis two ,(2001)
K Van Doren, Y Gluzman, Efficient transformation of human fibroblasts by adenovirus-simian virus 40 recombinants. Molecular and Cellular Biology. ,vol. 4, pp. 1653- 1656 ,(1984) , 10.1128/MCB.4.8.1653
Tobias Doerks, Amos Bairoch, Peer Bork, Protein annotation: detective work for function prediction Trends in Genetics. ,vol. 14, pp. 248- 250 ,(1998) , 10.1016/S0168-9525(98)01486-3
D L Longo, G L Gusella, I Espinoza-Delgado, L Varesio, Regulation of IL-2 receptor subunit genes in human monocytes. Differential effects of IL-2 and IFN-gamma. Journal of Immunology. ,vol. 149, pp. 2961- 2968 ,(1992)
Philip L. Felgner, Gary H. Rhodes, Robert Wallace Malone, Jon Asher Wolff, Dennis A. Carson, Expression of exogenous polynucleotide sequences in a vertebrate ,(1990)
Randal J. Kaufman, Vectors used for expression in mammalian cells. Methods in Enzymology. ,vol. 185, pp. 487- 511 ,(1990) , 10.1016/0076-6879(90)85041-L
Hongping Jiang, Zao-Zhong Su, P. B. Fisher, Jiao Jiao Lin, N. I. Goldstein, Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression. Oncogene. ,vol. 11, pp. 2477- 2486 ,(1995)
Michel Dreano, Richard Voellmy, Peter Bromley, Method for the in-vivo production and testing of proteins by recombinant gene expression in selected host-cells ,(1989)
Fei Huang, Jennifer Adelman, Hongping Jiang, Neil I Goldstein, Paul B Fisher, Identification and temporal expression pattern of genes modulated during irreversible growth arrest and terminal differentiation in human melanoma cells. Oncogene. ,vol. 18, pp. 3546- 3552 ,(1999) , 10.1038/SJ.ONC.1202715