Proteomics and transcriptomics investigation on longissimus muscles in Large White and Casertana pig breeds

作者: Leonardo Murgiano , Angelo D’Alessandro , Maria Giulia Egidi , Alessandra Crisa , Gianluca Prosperini

DOI: 10.1021/PR100693H

关键词:

摘要: Consumer complaints against the blandness of modern lean meat and frequent reference to more strongly flavored that was available years ago have prompted reconsideration high fat-depositing typical pig breeds. Casertana Large White breeds are characterized by a different tendency toward fat accumulation as they exhibit opposite genetic physiological traits with respect energy metabolism. These differences were investigated in longissimus lumborum muscles through proteomics (2-DE, MS/MS) microarray approaches. Data analyzed for pathway network analyses, well GO term enrichment biological functions. As result, showed greater amount proteins involved glycolitic metabolism mainly rely on fast-mobilizable sources. overexpressed cell cycle skeletal muscle growth related genes. Metabolic behavior other implications discussed.

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