The effect of tuberculosis control in China. Comment

摘要: Background China has 1 . 4 million new cases of tuberculosis every year, more than any country except India. A control project based on short-course chemotherapy was introduced in half the 1991, after a national survey prevalence 1990. Another done 2000 to re-evaluate burden, providing opportunity assess effect project. Methods The identified 375 599 eligible individuals at 257 investigation points chosen from all 31 mainland provinces by stratified random sampling. Children (aged 0-14 years) were suspected having if they had an induration 10 mm or greater tuberculin skin test, and abnormal fluorograph. Adults persistent cough, fluorograph, both. Tuberculosis diagnosed chest radiograph, sputum-smear microscopy, culture. Findings 365097 people examined (97% those eligible). Prevalences pulmonary, culture-positive, smear-positive 367 (95% CI 340-397), 160 (144-177), 122 (110-137) per 100000 population, respectively. Between 1990 2000, prevalences these three forms disease fallen, respectively, 32% (5-68), 37% (7-66), (9-51) areas which implemented non-project areas. For culture-positive disease, 30% (9-48) reduction directly attributable Interpretation 1991 reduced significantly use following WHO guidelines. We estimate that population billion, there 382 000 fewer prevalent 280 would otherwise have been.