Intralesional bleomycin sclerotherapy in childhood lymphangioma.

作者: Hoşgör M , Örnek Y , Demircan Y , Okur Ö , Aksoy N

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摘要: This clinical trial was conducted to evaluate the efficacy of intralesional bleomycin sclerotherapy (IBS) in children with lymphangioma and determine incidence complications treatment. Seventeen cases were treated IBS from 2004 2012. Age, mode presentation, locations types lesions, results treatment studied. Lymphangioma diagnosed by physical examination imaging studies. Most lesions located cervical region (n=8) macrocystic type (n=13). After first injection, three patients lost follow-up. Good response seen 50% complete resolution 35.7%, poor 14.3%. No serious or side effects observed after IBS. The average follow-up 18.5 months. is effective lymphangioma. Although no major adverse have been encountered, should be kept mind event their occurrence immediately.

参考文章(19)
G. Bruera, Enrico Ricevuto, P. Marchetti, General principles of chemotherapy. European Review for Medical and Pharmacological Sciences. ,vol. 14, pp. 269- 271 ,(2010)
M A Zulfiqar, R R Thambidorai, A M Zaleha, Z Zakaria, Z Rozman, Lymphangioma: Is intralesional bleomycin sclerotherapy effective? Biomedical Imaging and Intervention Journal. ,vol. 7, pp. 1- 8 ,(2011) , 10.2349/BIIJ.7.3.E18
David G. Poplack, Philip A. Pizzo, Principles and Practice of Pediatric Oncology ,(1989)
Jean-Yves Sichel, Raphael Udassin, David Gozal, Benjamin Z. Koplewitz, Itszhak Dano, Ron Eliashar, OK-432 therapy for cervical lymphangioma. Laryngoscope. ,vol. 114, pp. 1805- 1809 ,(2004) , 10.1097/00005537-200410000-00024
A Alqahtani, L.T Nguyen, H Flageole, K Shaw, J.-M Laberge, 25 years' experience with lymphangiomas in children. Journal of Pediatric Surgery. ,vol. 34, pp. 1164- 1168 ,(1999) , 10.1016/S0022-3468(99)90590-0
Shuhei Ogita, Toshiaki Tsuto, Kaori Nakamura, Eiichi Deguchi, Naomi Iwai, OK-432 therapy in 64 patients with lymphangioma. Journal of Pediatric Surgery. ,vol. 29, pp. 784- 785 ,(1994) , 10.1016/0022-3468(94)90370-0
Akira Okada, Akio Kubota, Masahiro Fukuzawa, Kenji Imura, Shinkichi Kamata, Injection of bleomycin as a primary therapy of cystic lymphangioma Journal of Pediatric Surgery. ,vol. 27, pp. 440- 443 ,(1992) , 10.1016/0022-3468(92)90331-Z
Nobuhiko Tanigawa, Takumi Shimomatsuya, Kohji Takahashi, Yukihiro Inomata, Koichi Tanaka, Kisaku Satomura, Yorinori Hikasa, Mitsuru Hashida, Shozo Muranishi, Hitoshi Sezaki, Treatment of cystic hygroma and lymphangioma with the use of bleomycin fat emulsion Cancer. ,vol. 60, pp. 741- 749 ,(1987) , 10.1002/1097-0142(19870815)60:4<741::AID-CNCR2820600406>3.0.CO;2-2
P. J. Emery, C. M. Bailey, J. N. G. Evans, Cystic hygroma of the head and neck. A review of 37 cases. Journal of Laryngology and Otology. ,vol. 98, pp. 613- 619 ,(1984) , 10.1017/S0022215100147176
C Luzzatto, Sclerosing treatment of lymphangiomas with OK-432 Archives of Disease in Childhood. ,vol. 82, pp. 316- 318 ,(2000) , 10.1136/ADC.82.4.316