A retrospective epidemiological study on the association of bullous pemphigoid and neurological diseases.

作者: Giuseppe Stinco , Rolando Codutti , Marco Scarbolo , Francesca Valent , Pasquale Patrone

DOI: 10.1080/00015550410024481

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摘要: Bullous pemphigoid is a rare chronic recurrent dermatosis that often reported in association with various neurological diseases. No investigation involving large number of patients has ever been carried out to demonstrate such an association. This study was accomplished by analysing the discharge diagnosis all hospitalized patients, both day-patients and inpatients, during 5-year period (1995-2000) covering total population group 934,023 living region Italy approximately 1,200,000 inhabitants. The results support hypothesis between bullous pemphigoid, multiple sclerosis Parkinson's disease on highly significant statistical basis. aetiopathogenic mechanisms causes induce loss immunological tolerance are not yet understood.

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