Recruiting adaptive cellular stress responses for successful brain ageing
作者： Alexis M. Stranahan , Mark P. Mattson
DOI: 10.1038/NRN3151
关键词:
摘要: Successful ageing is determined in part by genetic background, but also experiential factors associated with lifestyle and culture. Dietary, behavioural pharmacological interventions have been identified as potential means to slow brain forestall neurodegenerative disease. Many of these recruit adaptive cellular stress responses strengthen neuronal networks enhance plasticity. In this Science Society article, we describe several determinants healthy pathological ageing, insights into how processes are accelerated or prevented. We the mechanisms underlying neuroprotective actions exercise nutritional interventions, goal recruiting molecular targets for treatment prevention
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