Human metapneumovirus and respiratory syncytial virus in hospitalized danish children with acute respiratory tract infection.

作者: Marie-Louise von Linstow , Hans Henrik Larsen , Jesper Eugen-Olsen , Anders Koch , Thilde nordmann winther

DOI: 10.1080/00365540410018166

关键词:

摘要: The newly discovered human metapneumovirus (hMPV) has been shown to be associated with respiratory illness. We determined the frequencies and clinical features of hMPV syncytial virus (RSV) infections in 374 Danish children 383 episodes acute tract infection (ARTI). Study material comprised routine nasopharyngeal aspirates obtained during 2 winter seasons (November-May) 1999-2000 2001-2002 from hospitalized at Departments Paediatrics, Hvidovre Hospital Amager Hospital, Denmark. was detected 11 (2.9%) RSV 190 (49.6%) ARTI by real-time reverse transcription-polymerase chain reaction using primers targeting N gene L gene. Two were co-infected RSV. They excluded statistical analysis. Hospitalization for caused restricted very young 1-6 months age. Asthmatic bronchitis diagnosed 66.7% 10.6% RSV-infected (p < 0.001). Overall symptoms findings similar among positive episodes, but more required support. is present although less frequent than a tendency milder course.

参考文章(26)
Michael D Nissen, Ian M Mackay, Stephen J Withers, David J Siebert, Theo P Sloots, Evidence of human metapneumovirus in Australian children. The Medical Journal of Australia. ,vol. 176, pp. 188- 188 ,(2002) , 10.5694/J.1326-5377.2002.TB04354.X
J.S. Malik Peiris, Wing-Hong Tang, Kwok-Hung Chan, Pek-Lan Khong, Yi Guan, Yu-Lung Lau, Susan S. Chiu, Children with respiratory disease associated with metapneumovirus in Hong Kong. Emerging Infectious Diseases. ,vol. 9, pp. 628- 633 ,(2003) , 10.3201/EID0906.030009
Julie Greensill, Paul S. McNamara, Winifred Dove, Brian Flanagan, Rosalind L. Smyth, C. Anthony Hart, Human Metapneumovirus in Severe Respiratory Syncytial Virus Bronchiolitis Emerging Infectious Diseases. ,vol. 9, pp. 372- 375 ,(2003) , 10.3201/EID0903.020289
Diego Vicente, Gustavo Cilla, Milagros Montes, Emilio Pérez-Trallero, Human Metapneumovirus and Community-Acquired Respiratory Illness in Children Emerging Infectious Diseases. ,vol. 9, pp. 602- 603 ,(2003) , 10.3201/EID0905.020615
Takashi Ebihara, Rika Endo, Hideaki Kikuta, Nobuhisa Ishiguro, Mikio Yoshioka, Xiaoming Ma, Kunihiko Kobayashi, Seroprevalence of human metapneumovirus in Japan. Journal of Medical Virology. ,vol. 70, pp. 281- 283 ,(2003) , 10.1002/JMV.10391
Henrik D??llner, Kari Risnes, Andreas Radtke, Svein Arne Nordb??, Outbreak of human metapneumovirus infection in norwegian children. Pediatric Infectious Disease Journal. ,vol. 23, pp. 436- 440 ,(2004) , 10.1097/01.INF.0000126401.21779.74
Joanne Stockton, Iain Stephenson, Douglas Fleming, Maria Zambon, Human metapneumovirus as a cause of community-acquired respiratory illness Emerging Infectious Diseases. ,vol. 8, pp. 897- 901 ,(2002) , 10.3201/EID0809.020084
Tuomas Jartti, Bernadette van den Hoogen, Roberto P Garofalo, Albert DME Osterhaus, Olli Ruuskanen, Metapneumovirus and acute wheezing in children The Lancet. ,vol. 360, pp. 1393- 1394 ,(2002) , 10.1016/S0140-6736(02)11391-2
S. Viazov, F. Ratjen, R. Scheidhauer, M. Fiedler, M. Roggendorf, High Prevalence of Human Metapneumovirus Infection in Young Children and Genetic Heterogeneity of the Viral Isolates Journal of Clinical Microbiology. ,vol. 41, pp. 3043- 3045 ,(2003) , 10.1128/JCM.41.7.3043-3045.2003